What we have here are two Pickups from Ford with some differences, such as the horsepower and ground shadow size. First of all, the 2016 Ford F-250 Super Duty Crew Cab pulls more horsepower than the 2016 Ford F-350 Super Duty Crew Cab. And finally, the body structure of 2016 F-250 Super Duty Crew Cab is slightly smaller than that of the 2016 F-350 Super Duty Crew Cab. Among similarities are the body structure, starting price, height, and maximum occupancy.