What we have here are two Sedans from Lexus with some differences, such as the horsepower, fuel economy, model year, and market segment. First of all, there is a difference in model years. The is 2 years newer. Also, the 2014 IS 350 has a more powerful engine than the 2016 ES 300h, and it gets 18.5 fewer miles on a gallon of fuel. Among similarities are the body structure, market segment, starting price, ground shadow size, height, and maximum occupancy.