Two SUVs with some similarities, but otherwise different in most aspects such as the model year, market segment, horsepower, fuel economy, and maximum occupancy. First of all, the 2016 RX 350 has a more powerful engine than the 2013 Highlander Hybrid, and it gets 5.5 fewer miles on a gallon of fuel. Also, you'll seat two more passengers in the Highlander Hybrid than in the RX 350. Among similarities are the body structure, starting price, ground shadow size, and height.