2016 Mercedes-Benz S-Class Sedan is the newer version with some differences, such as the model year, horsepower, and fuel economy.. First of all, the is a newer vehicle by 3 model years. And finally, the 2016 S-Class Sedan has a more powerful engine than the 2013 S-Class, but it gets 1.3 more miles on a gallon of fuel. Among similarities are the body structure, market segment, starting price, ground shadow size, height, and maximum occupancy.