Although there are some similarities, these two are different in most aspects such as body structure, powertrain, fuel economy, market segment, and starting price. First of all, these two have similarly-sized dimensions, even though one is an SUV and the other a Sedan. Also, the 2017 Cayenne Hybrid, being a hybrid, gets 78.1 more miles on a gallon than the 2017 Model S. In addition, there is a notable difference in the starting price of the Model S, which is $10,700 less than the base MSRP of the Cayenne Hybrid. Among similarities are the market segment, ground shadow size, and maximum occupancy.